I-SIFI IMEMEZELA UKWETHULWA KWE-EPICOLIN, UKUSEKELWA OKUGCWELE EKWELASHWENI KWE-GLAUCOMA

I-SIFI, inkampani ehamba phambili eyenza imithi ekuthuthukiseni izixazululo ezintsha zokwelapha izifo zamehlo, iyajabula ukumemezela ukwethulwa kwe-EpiColin, ukusekelwa okuphelele okunikezelwe ezigulini eziphethwe yi-glaucoma.

I-SIFI, inkampani ehamba phambili eyenza imithi ekuthuthukiseni izixazululo ezintsha zokwelapha izifo zamehlo, kuyakuthokozela ukumemezela ukwethulwa kwe-EpiColin, ukwesekwa okuphelele kweziguli ze-glaucoma. Ngemuva kwe-Amiriox ne-Ecbirio, izidakamizwa ze-hypotonizing zibuyiselwe ngokuphelele yi-NHS, I-EpiColin ingeyesithathu emisha endaweni yokwelapha i-glaucoma yethulwe yi-SIFI engxenyeni yesibili ka-2022.

Iyini i-Epicolin

EpiColin a isengezo sokudla okusekelwe ezitshalweni ze-Coleus forskohlii netiye eliluhlaza, eline-citicoline, i-homotaurine, amavithamini eqembu B kanye novithamini E, okuyisithasiselo esibalulekile ekwelapheni kwe-hypotonizing ekulawuleni i-glaucoma, isifo esingamahlalakhona esiwohlokayo.

"Manje sekuyaziwa ukuthi umfutho wamehlo akuyona ukuphela kwengozi yokuqhubekela phambili kwe-glaucoma." wamemezela i UDkt Matteo Sacchi, iNhloko ye-Glaucoma Centre ye-University Eye Clinic, esibhedlela sase-San Giuseppe -IRCCS MultiMedica, eMilan, kanye nengqungquthela kazwelonke yakamuva enikezelwe ekwelapheni i-glaucoma, "Ukunakwa okukhulayo manje kuphinde kubekwe ezicini ezifana nokucindezeleka kwe-oxidative, i-neuroinflammation kanye nokungasebenzi kahle kwe-mitochondrial, okuqinisekisa ukubaluleka kwendlela entsha yokwelapha ye-synergistic ehlanganisa umbono wesikhathi esifushane nesikhathi eside wesiguli."

Ezigulini ezine-glaucoma, lesi sifo singaqhubeka naphezu kokuncipha kwengcindezi ye-intra-ocular^1-3, futhi ngakho-ke kuyadingeka ukusekela ukwelashwa ukuze kuvinjwe noma kubambezeleke le nqubo yokuwohloka kwamangqamuzana e-retina^4,5. I-EpiColin Therapeutic supplementation ephelele yakhelwe ukukhiqiza umphumela obalulekile we-neuroprotective kanye ne-antioxidant ngenxa yesenzo sokusebenzisana sezakhi ngazinye, ezaziwa futhi ezinokwethenjelwa, ekusekeleni ukwelashwa kwe-hypotonizing. Umphumela we-neuroprotective we-nutraceuticals ukhonjisiwe kokubili ezifundweni ze-preclinical in vitro kanye ne-vivo, nasezifundweni zomtholampilo.⁶.

Ngokwezilinganiso zakamuva e-Italy kuneziguli eziqinisekisiwe ezibalelwa ku-550.000 ezine-glaucoma ezinezigameko ezikhula ngokukhula, ezithinta ngaphezu kwe-10% yezifundo ezingaphezu kweminyaka engama-70 ubudala. Kulinganiselwa ukuthi eminyakeni engama-20 ezayo kuzoba nokunyuka okungama-33% kwamacala aqinisekisiwe e-Italy ngeziqongo ezingama-50% ezifundeni lapho kulindeleke khona ukuguga okubaluleke kakhulu.^7_.

glaucoma

I-glaucoma yisifo samehlo ngokuvamile esihlobene nokucindezela okukhulu kakhulu kweso. Ngokwe-WHO, babalelwa ezigidini ezingama-60 abantu abathintekile emhlabeni jikelele⁸. Kuyimbangela yesibili yobumpumputhe emhlabeni wonke ngemva kolwelwesi lwamehlo, kodwa ingeyokuqala engenakuguqulwa⁹.

I-AMIRIOX™ ne-ECBIIO™ I-Amiriox™ (i-bimatoprost 0,3 mg/ml) ne-Ecbirio™ (i-bimatoprost 0,3 mg/ml + timolol 5 mg/ml) ngokulandelana, i-monotherapy entsha kanye namaconsi enhlanganisela ahlanganisiwe agunyazwe ukunciphisa umfutho ophakeme we-intraocular ku-engeli evulekile engapheli. iziguli ezine-glaucoma kanye ne-ocular hypertension. I-Amiriox™ ne-Ecbirio™ zitholakala ngendlela engasebenzisi i-preservative multidose egcina i-ocular surface, esebenza kuze kube yizinyanga ezintathu ngemva kokuvulwa.

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